Revolutionizing Gene Therapy Manufacturing: Robotics And Machine Learning For Process Intensification

Transforming viral vector production

Despite recent advancements in gene therapies, the industry continues to face significant challenges, including extended development timelines and high manufacturing costs. To help address these barriers in the production of viral vectors used in gene therapy applications, Thermo Fisher has developed an integrated approach leveraging machine learning, high throughput process and analytical development, and perfusion intensification. This advanced production ecosystem has been successfully implemented at bench and up to 2000L scales, demonstrating its suitability for the large scale manufacturing needed to support increasing clinical demand for gene therapies.

Watch this webinar to explore the future-focused strategies reshaping gene therapy manufacturing. 

Register now to learn:

• Overview of high-throughput system that enables the screening of up to 100 bioreactor production conditions per week, including purification steps and analytical tests
• Utilization of machine learning combined with mechanistic modeling to predict upstream productivity
• Integration of perfusion into upstream production to realize up to fivefold increase in productivity, enabling titers that far exceed industry benchmarks

Meet the Speaker

Pouria Motevalian, Ph.D.

Director, Bioprocess Sciences
at Thermo Fisher Scientific

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